Chlorella & Cilantro Heavy Metal Detox Protocols


By Cat, Feb 2019 (moved from Detox from Toxic Heavy Metals); image, right, from Wikimedia Commons

I continue to try new protocols for my mercury toxicity, but so far, this protocol is my favorite. How did I get mercury toxicity? I grew up in the 1950s, and was exposed to mercury from:

  • silver amalgam tooth fillings;
  • using mercurochrome to heal cuts when I was a child;
  • playing with mercury “marbles,” and
  • certain lab experiments in graduate school that involved inhaling mercury.

Detox (detoxification) is “the physiological or medicinal removal of toxic substances from a living organism, including the human body, which is mainly carried out by the liver.” (11)

Some heavy metals are good for you (up to a point), such as copper, iron, selenium, zinc, and more. For these, it is best to take them in chelated form, such as bound to a protein, peptide or amino acid). Taking them in their ionized (salt) form, can be harmful (for example: sodium selenate, zinc chloride, zinc phosphate). Others are quite toxic (no matter how you are exposed to them), such as aluminum, lead and mercury.

Chlorella & Cilantro with Vitamin C for heavy metal detox

This is the first ‘natural’ protocol I tried for mercury toxicity, when I developed a food sensitivity to DMSA. It is basically a two-step protocol (Chlorella and Cilantro), but additional recommendations have since been added. NOTE: take the Chlorella first, followed by Cilantro; then Vitamin C several hours later. See Sample Chelation Schedule, below.

  1. Step 1: Cilantro tincture mobilizes mercury out of the cells and into the bloodstream;
  2. Step 2: Chlorella powder or tablets binds mercury in the blood and excrete it with the stool. It binds only toxic metals, not essential ones (8H)
  3. Step 3 (optional): Vitamin C (ascorbic acid) can also be taken with the protocol, to boost levels of glutathione, a powerful detox agent in the liver.

Dosage and scheduling

The following is from Curezone: Cilantro/Chlorella/Vitamin C Chelate Mercury (11), also from The Klinghardt Neurotoxin Elimination Protocol (12A)

  • Chlorella (binder): Take this first (before cilantro), so it is available in the blood as soon as cilantro teases the heavy metals out of hiding. For general use, best taken with meals in small doses throughout the day, totaling 3 – 5 grams (1 tsp powder = 5 g). For chelation therapy, use 5 grams (1 tsp) of chlorella powder or one 5g tablet per day; this can be in divided doses taken 30 minutes before the cilantro.  Avoid taking before or after a caffeinated or soft drink beverage. See Healing Daily (24) for more about using chlorella to detox mercury. At first, I added chlorella powder to my morning smoothie, but it ruined the taste, so I switched to chlorella tablets.
  • NOTE: Chlorella has evolved to bind ONLY toxic minerals, not ones that are essential, such as magnesium, calcium, etc. See Mercola (8H) for more.
  • Cilantro (mobilizer): Start with 2 drops cilantro tincture, 2 times per day in the beginning, increasing to 10 drops 2 times/day for full benefit. Take just before a meal or 30 minutes after taking chlorella.
  • Vitamin C: Take as far away from chlorella as possible (best after meals). 500 mg per day or more can be taken (I take 500 mg 3-times per day in my whole-food multi-vitamin). There are two forms: ascorbic acid or ascorbate (mineralized). During the chelating days, the acid form is best; during the remineralization-days, the mineralized form, such as magnesium ascorbate, is best.
  • Butyrate: (4-carbon fatty acid from butter).
    • I started with Butyrex, which includes magnesium and other mineral salts (Amazon ASIN B003JOJ04G). It contains 600 mg butyric acid per capsule, with magnesium taurate salt. Recommended dose: 1-2 caps, 3x daily (1800 – 3600 mg/day).
    • Another option: Butyr-En (iHerb code ALG-70220), contains 100 mg butyric acid per capsule as a calcium-magnesium salt).  Recommended dose: 1-2 caps, 3x daily (300 – 600 mg/day). Not sure why this is so much less than Butyrex dose.
    • I’ve since switched to Tributrin (Butycaps brand, Amazon ASIN B077BLKJCX), after I started having food sensitivity issues to magnesium; each packet contains 787 mg butyric acid. Tributrin is the natural tributyrate from butter; I also eat a fair amount of butter daily. I regularly take 1 Butycap packet daily, added to my smoothie, but when doing detox protocol I take 2 packets daily (or 1 packet plus 1 capsule Butyrex), plus plenty of dietary butter.

Butyric acid/butyrate is anti-inflammatory and protects the colon from free-radicals, helping to prevent colon cancer. If you have a healthy gut microbiome, the good bugs in your gut will make enough butyrate (from carbs) for good health. But if you have heavy metal or other toxicity issues, your gut balance is off and you can benefit from supplemental butyric acid/butyrate. It helps clean the liver, the gall bladder, and biliary tree in the liver. It also helps clean the bowel, helps control ammonia, and removes unwanted “renegade fats”. See Paleo Leap (25) and Center for Wellness (26) for more.

Two stages: Chelation and Re-mineralization:

  • Chelation: Each day of chelation therapy, avoid all supplemental sources of minerals, as they will be chelated instead of the toxic minerals.
  • Re-mineralization: Do this on days you are not chelating; see Other Considerations: Mineralization, below for more.

Note: If you do chelation every day, you will overwhelm your body. Instead, do:

  • 1 week chelation, then 2 – 3 weeks re-mineralizing is recommended; OR
  • 2-week cycles as: 2 days chelation, and 12 days re-mineralizing; this is what I do so I don’t have to go a whole week without my essential magnesium. However, I’ve since learned that chlorella does not bind magnesium so this should not be a problem

Sample chelation schedule & dosage

  1. Breakfast- and Dinner-time:
    • Chlorella: half-dose or 2.5 g (1/2 tsp) 30 minutes before breakfast/dinner and/or before coffee;
    • Cilantro: 2 drops (increase to 10 drops over time) after the chlorella (before breakfast) or 30 minutes after breakfast/dinner;
    • Vitamin C: after breakfast is complete, or wait until after lunch;
  2. Lunch-time:
      • No chlorella/cilantro;
      • vitamin C: can take after lunch;

Additional foods/supplements to support the chlorella/cilantro therapy:

  1. Garlic/wild garlic are also recommended with this protocol:
    • to protect white and red blood cells from oxidative damage (by toxic heavy metals), and
    • because of allicin’s antimicrobial ability against secondary infections common with metal toxicity.
    • Dosage: 1–3 capsules freeze dried garlic after each meal. Start with 1 capsule after the main meal per day; slowly increase to the higher dosage. Initially the patient may experience die-off reactions (from killing pathogenic fungal or bacterial organisms). Use 5–10 drops bear-garlic on food at least 3 times per day. (Klinghardt protocol, (6))
  2. Fish oil is also recommended with this protocol. It:
    • Contains EPA and DHA which protect the brain from viral infections;
    • Makes white and red blood cell more flexible, improving micro-circulation of the brain, heart and other tissues.
    • Dosage: 1 capsule (or 1 serving or liquid) Omega 3 or fish oil taken 4 times/day during the active phase of treatment; 1 capsule (or 1 serving or liquid) twice/day for maintenance. Best if taken together with chlorella. (6)
  3. Natural ocean salt (such as Celtic sea salt or Himalayan sea salt) instead of table salt:
    • It helps with hydration, and with proper reception of electric messages in the body’s autonomic nervous system.
    • Even better is a specific electrolyte formula developed by the American chemist Ketkovsky and improved by Morin Labs, now called “selectrolyte.”
    • Dosage: 1 tsp in a cup of good water 1–3 times/day. During times of greater stress the dosage can be temporarily increased to 1 tbsp 3 times/day. (6) See also Zeta-Aid (7)

Other considerations: When to take/not to take mineral supplements (with chlorella/cilantro detox)

It is important to remember that the chelating agent will not only grab the toxic heavy metals, but also vital minerals your body needs.  For example, calcium, iron, magnesium, and zinc are all vulnerable to the chelator.  Therefore, it is advisable to refrain from taking mineral supplements beginning 12-18 hours before dosing with chelating agent until the afternoon of the day following the dose. If you do not do this, the chelator will simply pick up the minerals from the supplement and not touch the embedded toxic metals. Example schedule, Sunday – Tuesday:

  • Sunday, After 2 PM: cease taking any mineral supplement;
  • Monday 8 AM: take the chelator. If you wish to take the chelator several days in a row, do not resume mineral supplementation until 3 PM the next day after you cease taking the chelator;
  • Tuesday (or the day after you stop taking the chelator), after 3 PM: you can resume mineral supplementation; i.e., remineralization (see below).

This ability of the chelator to remove essential minerals could have a silver lining:  It could remove them from hiding where they are not wanted (such as calcified arterial plaque); then when you remineralize after chelation, they could be restored to where they are wanted, (such as calcium to bone tissue).

Remineralization:It is very important to remineralize as instructed, after the dosing period, to restore your levels of essential and trace minerals.  It’s a good idea to take mineral supplements with a glass of raw milk or kefir, or a bowl of unsweetened yogurt, as the raw or cultured dairy products increase the absorption of the minerals.  Also a good idea to take some fish oil or cod liver oil at the same time, as the fats also increase the absorption. (I do both of these when I drink my morning smoothie).

In addition to taking mineral supplements, also drink plenty of filtered or distilled water that has been remineralized by adding clay or other mineral source (see Detox with Bentonite clay, above). Or you can drink unfiltered water if you have had it tested and know it is free of heavy metal contamination and chlorine.

Mineral supplements:

  • ConcenTrace is a liquid mineral source from pure sea water (with the sodium removed), available from Radiant Lie ( available on Radiant Life (9))
  • Ancient Earth Minerals (available on Live Superfoods),
  • Vital Earth Fulvic-Humic Mineral Complex (iHerb code VEM-00003),
  • Azomite is a certified organic, natural trace mineral fertilizer, but can also be added to water to take supplementally
  • Unrefined sea salt, such as Real Salt or Celtic sea salt should be used instead of table salt

My experience/notes regarding chlorella/cilantro protocol

As with prescription chelators, the cilantro/chlorella combo should not be done every day. 1 week on and 2 – 3 weeks off is recommended. See Curezone: Cilantro/Chlorella/Vitamin-C Chelate Mercury (27) for more. Cat’s dilemma: I can’t go a whole week without MgCl2 supplementation (during chelation) so I’ve modified this to using chelator 2 days on, 12 days off (which means my minerals are 2 days off, 12 days on at my usual dose of 2 droppers-full 80% MgCl2 solution, 3x daily.

The Kitchen Doctor (28) also has some good info on this, although I somewhat disagree with his take on candida and parasites (he says they increase when you remove mercury, but my experience is that mercury tends to protect candida (candida may decrease when you remove mercury).

I started mixing powdered chlorella with my smoothie, but I did not care for its flavor. Instead, I would prefer to take the chlorella tablets.

Mercola’s Mercury Detox Protocol 

This protocol (8c) is used in conjunction with DMPS chelation therapy; however, it could be done without the DMPS (see Chlorella & Cilantro with Vitamin C protocol, above).

My preference is to do just the Chlorella & Cilantro with Vitamin C protocol (above), but follow Mercola’s dietary and other suggestions.

It combines two chelating protocols: 

  • DMSA or DMPS are synthetic agents that perform a dual duty: they lure the metals out of your tissues, chelate them, and carry them out of the body;
  • Chlorella and cilantro agents (see also Chlorella and Cilantro with Vitamin C Protocol, above): Cilantro (tincture) mobilizes the toxins from tissues to the blood stream; chlorella (powder or pill) is a binding agent that carries them out of the body via urine and feces. A caution, from Natural Science (17): Chlorella “mobilizes more toxins then it can carry out of the body, it may flood the connective tissue (where the nerves reside) with metals, that were previously stored in safer hiding places. This can cause re-toxification if another binding agent isn’t used to help rid the body of the heavy metals that are ‘found’ in their hiding places throughout the body.”

Additional supplements that assist the chelation are:

  • MSM (another I cannot use because of sensitivity issues with sulfur), daily mineral supplement; and
  • Butyrate (important short-chain fatty acid for which butter is named). Cat’s note: I use lots of real butter in my daily diet, and add a tributrin supplement (Buty-Caps) to my daily smoothie (tributrin is the form of butyric acid in butter).

This protocol recommends starting with one 500 mg tablet chlorella daily to determine if you have any problems with it. Then increase over 1-2 weeks to a dose of 10 tablets daily (total 5 g/day), or same dose as combo of tablets and powder. Adding 1 tablet each day over 10 days would accomplish this. This is for a 150 lb person. Caution: if you start burping-up the chlorella taste, you are developing a sensitivity and should stop immediately. Then switch to ProChitosan (see item 4 in list below).

See also NIHA article (18) for more information on dosing chlorella and cilantro.

Summary of Mercola’s protocol (see his article for more details (8C):

  1. Diet: Avoid all sugar and milk (but whey protein powder can be used), limit all processed foods and most grains, especially wheat.
  2. Beneficial Bacteria: “Take one quarter to one half teaspoon once a day of a high potency high quality strain. It is vital to have an optimized bowel flora for detoxification.” I use 1 capsules Mercola’s Spore Restore (iHerb MCL-01885) and 2 capsule of Mercola’s Complete Probiotics (iHerb MCL-01317) daily during the detox period.
  3. Maintain two to three bowel movements per day:I take magnesium chloride (as 80% solution from my local compounding pharmacy) to help with this, as I have constipation without this important supplement. I also add freshly ground flax seeds to my daily smoothie.
  4. Unload the connective tissue with Chlorella or ProChitosan: I use chlorella, but don’t take it every day except during the “On” weeks of the detox. Mercola adds a  “Caution: If at any time one develops nausea or starts “burping up” the chlorella taste then the chlorella should be stopped immediately as a food sensitivity is developing which will only worsen if you continue taking it. If this happens you should switch to ProChitosan. This binds similarly to mercury. Its dose is dependent on your bowel movements.” I am not familiar with ProChitosan and cannot find a source. Another alternative is Porphrazyme from Biotics Research (38).
  5. Garlic (3 cloves/day, not a supplement) or MSM for your sulfur stores.
  6. Cilantro helps mobilize mercury out of your tissues. Always take it AFTER chlorella or other binder. Mercola recommends a tincture from Dragon River (505-583-2348), but I get my tincture from Swan Valley Herbs in Bigfork.
  7. Mineral replacement: I get mine from daily dose of Mercola’s Whole Food Multi (iHerb MCL-01035 or MCL-01939 for women); and also hydrochloric acid (which I get from Betaine-HCL supplement)
  8. Digestion and gall bladder support (especially for autism): He recommends butyric acid and magnesium taurate, digestive enzymes including lipase, CCK (Cholecystokinin), and headful fats such as those from seeds, nuts, avocado, coconut oil, and free range organic poultry, eggs, or meats. Cat’s note: I take Tributyrin, the form of butyric acid in butter, healthful fats, and a liver-gal bladder support tincture from Swan Valley Herbs (dandelion root, milk thistle seed and burdock root); and also a digestive enzyme supplement that includes betaine (iHerb NOW-02964).
  9. Anti-oxidants, specifically Vitamins C and E. He recommends 250-500 mg of vitamin C with each meal, and 2000 units (typically five of the 400 unit capsules) of vitamin E the day of and the day after the DMPS injection as this will decrease the side effects of the detoxification reaction considerably.
  10. DMPS injections or an alternative. I have trouble with these so do not include DMSA nor DMPS because of my sensitivity issues with sulfur-containing compounds.

Other recommendations for mercury detox, with this protocol:

  • Vitamin B9 (as folate, not as folic acid): According to Mercola’s sales pitch for his folate supplement, it helps to “sweep away glyphosate [Roundup toxin] and heavy metals (8G). So eat good dietary sources (see Vitamin B Complex for ideas), and take a good quality methyl-folate supplement if you have either/both of these toxins.
  • Garlic (and other members of the onion family): Mercola recommends 3 cloves garlic/day. Or supplement with MSM, a sulfur compound (methyl-sulfonyl-methane).(8c). See also “Garlic for lead detox,” below, about study showing garlic is as effective at detoxing lead as a prescription drug, with fewer side effects.
  • Getting adequate essential minerals daily (especially magnesium, selenium and zinc, but avoid copper and iron supplements). However, do not take them while taking the agents, as they will bind the minerals so you can’t absorb them; instead, take these on the off-days. It’s important to monitor your mineral levels (blood test) every 6-12 weeks (2-3 months).
  • Getting adequate good dietary fats daily, as this promotes bile production and release from the gall bladder, essential to eliminating chelated heavy metals. for example, coconut oil, butter, true olive oil, fish oil and cod liver oil. (see my article Good Fats for Cooking for more). CCK (cholecystokinin) can also be taken to promote gall bladder contraction. Or coffee enemas.
  • Whey protein is also suggested to support your glutathione system. I recommend Bob’s Red Mill Whey Protein Powder, because it is dried at low temperatures to avoid denaturing the protein..
  • Milk thistle (13), which is healing for the liver. [I take this as part of my daily dose of Liver tincture complex from Swan Valley Herbs.]
  • Livaplex (1-2 caps/day) and Antronex (1 table/day) from Standard Process, to support the liver (only available through practitioners).
  • Saunas are also recommended, or at least hot sweating baths.
  • Pure water: Drink LOTS of pure (filtered) water daily.


References 1 – 37 are copied (2/10/20) from Detox from Toxic Heavy Metals reference list; references beginning with 38, have been added specifically for this article.

  1. Wellness Education Center (WEC), Kalispell MT
  2. A Breakthrough in Cell Detoxification, from Dr. Dan Pompa (
  3. Jonathan Landsman article:
  4. Wendy Myers:
    1. On NanoVi detox device:
    2. on mitochondria detox:
    3. on sugar detox:  Sugar 101 and 10 min Video
  5. Catherine Haug article: How to Detox Glyphosate ( Roundup) from your Body
  6. The Klinghardt Neurotoxin Elimination Protocol (
  7. About Zeta-aid:
  8. Mercola articles:
    1. Richard johnson interview:(
    2. What is NADPH and NOX (
    3. Detox protocol:
    4. Interview with Dr. Klinghardt on mercury elimination:
    5. Mercola on “Three Pillars of Heavy Metal Detoxification (8e) (
    6. Mercola and Dr. Shade on
    7. Folate sales pitch:
  9. Journal of Biological Physics and Chemistry
  10. How to Detox Glyphosate ( Roundup) from your Body (by Cat)
  11. Meaning of detox from Wikipedia (
  12. Dr Axe:
    1. on chelating agents (
    2. on humic/fulvic acids (
  13. Gaiam blog:
  14. Wellness Mama:
  15. TTAC:
  16. Wikipedia:
  17. Natural Society:
  18. National Integrated Health Associates: (site requires signing a disclaimer before allowing access
  19. Travis Wade Fitness: (link no longer valid)
  20. Green Med Info:
    1. Mixing Instructions for Living Clay (
    2. Articles about Living Clay:
  23. Yerba Prima’s Great Plains Bentonite Detox, Liquid formula ( See also iHerb code YBP-00519
  24. Healing Daily (
  25. Paleo Leap (
  26. Center for Wellness (
  27. Curezone: Cilantro/Chlorella/Vitamin C Chelate Mercury (
  28. Kitchen Doctor (
  29. About Nrf2:
  30. GMOsRevealed email text (3/20/19)
  31. Organifi Gold powder for Golden Milk/Tea
  32. Well of Life (Jonathan Otto sales pitches):
  33. Wikipedia:
  35. Soil Biotics:
  37. Dr. Hagmire on EDTA Suppositories:
  38. Biotics Research product:

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